CompletedNot Applicable

Bisphenol A and Muscle Insulin Sensitivity

United States40 participantsStarted 2019-01-01

Plain-language summary

This study examine oral bisphenol A consumption on muscle insulin sensitivity and hepatic glucose suppression. Half of the participants will receive a diet plus BPA and the other half will receive a diet plus no bisphenol A.

Who can participate

Age range18 Years – 50 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * non-dieting * sedentary (≤3 hour/week of aerobic exercise) * normal-weight (BMI = 18.5 to 24.9 kg/m2) * weight-stable for the previous 6 months * free of any metabolic or chronic disease * non-smoking, and sedentary Exclusion Criteria: * Hemoglobin A1C based on the American Diabetes Association guidelines of 5.7 to 6.4% (Prediabetes) or \>6.4% (Diabetes) * impaired glucose tolerance * type 1 diabetes * type 2 diabetes * colitis or any inflammatory bowel condition * neurologic or psychiatric conditions * smoking * special diets (e.g. vegetarian, low-carbohydrate, Paleolithic, etc.) * pregnant women or women trying to become pregnant

What they're measuring

Change in rate of glucose disposal

Timeframe: Baseline and 4 days

Change in rate of glucose appearance

Timeframe: Baseline and 4 days

Trial details

NCT IDNCT03771066

SponsorCalifornia Polytechnic State University-San Luis Obispo

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-12-31

View on ClinicalTrials.gov More Insulin Sensitivity trials