CompletedNot Applicable

Trauma as a Trigger for Autoimmunity

Switzerland50 participantsStarted 2016-07-04

Plain-language summary

To analyse the immunological reaction to Trauma (pertrochanteric femoral fracture with consequent osteosynthesis) in the first weeks up to one year postoperatively with focus on the development of autoimmunity.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * pertrochanteric femoral fracture (≤7 days) * planned gamma nail osteosynthesis * ability to give written informed consent Exclusion Criteria: * Severe hepatic and renal failure * current active oncological disease * current immunosuppressive or biological therapy * known systemic autoimmune disease * foreseeable lack of complete follow-up (e.g. due to generally poor health) * cognitive impairment (delirium, dementia, alteration of consciousness) * insufficient knowledge of project language * pregnancy

What they're measuring

Change in ANA

Timeframe: Preoperative (1-2 days preoperative) and 12 weeks postoperative

Trial details

NCT IDNCT03767712

SponsorUniversity Hospital, Basel, Switzerland

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2019-12-23

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