Role of Dietary Protein Intake in Elderly Adults (NCT03765710) | Clinical Trial Compass
CompletedNot Applicable
Role of Dietary Protein Intake in Elderly Adults
8 participantsStarted 2015-08
Plain-language summary
The investigators examined the effects of dietary protein intake in a mixed meal at two levels of protein amount on whole body protein metabolisms in older adults.
Who can participate
Age range60 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Men and women, ages \> 60 years
Exclusion Criteria:
* History of diabetes
* History of malignancy in the 6 months prior to enrollment
* History of gastrointestinal bypass surgery (Lapband, etc)
* History of a chronic inflammatory condition or disease (Lupus, HIV/AIDS, etc)
* Pregnant females
* Subjects who do not or will not eat animal proteins
* Subjects who cannot refrain from consuming protein or amino acid supplements during their participation in this study
* Subjects who report regular resistance exercise (more than once per week)
* Hemoglobin less than 9.5 mg/dL at the screening visit
* Platelets less than 150,000 at the screening visit
* Subjects who are not willing or able to suspend aspirin for several days prior to their muscle biopsies
* Subjects who have been prescribed a blood-thinning medication (Coumadin, lovenox, heparin, Plavix, etc.)
* Concomitant use of corticosteroids (ingestion, injection or transdermal)
* Any other disease or condition that would place the subject at increased risk of harm if they were to participate, at the discretion of the study physician
What they're measuring
1
Changes in whole body anabolism
Timeframe: Change before and after a mixed meal intake for approximately 8 hours
2
Changes in skeletal muscle synthetic rate
Timeframe: Change before and after a mixed meal intake for approximately 8 hours