CompletedNot Applicable

Modification of Goal-directed and Habitual Behavior in Addiction

Germany75 participantsStarted 2020-01-07

Plain-language summary

This study aims to examine the modification of the hypothesized imbalance between goal-directed and habitual behavior and its neural correlates in smokers. Two interventions will be used as add-on trainings to a smoking cessation program.

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * severe tobacco use disorder (TUD) according to DSM-5 * sufficient ability to communicate with investigators and answer questions in both written and verbal format * ability to provide fully informed consent and to use self-rating scales Exclusion Criteria: * severe internal, neurological, and/or psychiatric comorbidities; other Axis I mental disorders other than TUD according to ICD-10 and DSM 5 (except for mild depression, i.e. F32.0, adjustment disorder and specific phobias) in the last 12 months * history of brain injury * severe physical diseases * common exclusion criteria for MRI (e.g. metal, claustrophobia) * positive drug screening (opioids, benzodiazepines, barbiturates, cocaine, amphetamines) * psychotropic medication within the last 14 days * pregnancy

What they're measuring

Change in imbalance between goal-directed and habitual behavior

Timeframe: 2 time points: before and after 6 weeks SCP

Change in implicit smoking-related associations

Timeframe: 3 time points: before and after 6 weeks SCP plus after 3 months

Change in attentional bias to smoking cues

Timeframe: 3 time points: before and after 6 weeks SCP plus after 3 months

Change in smoking urges

Timeframe: 3 time points: before and after 6 weeks SCP plus after 3 months

Change in working memory capacity

Timeframe: 3 time points: before and after 6 weeks SCP plus after 3 months

Change in planning ability

Timeframe: 3 time points: before and after 6 weeks SCP plus after 3 months

Change in cognitive flexibility

Timeframe: 3 time points: before and after 6 weeks SCP plus after 3 months

Trial details

NCT IDNCT03764969

SponsorCentral Institute of Mental Health, Mannheim

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-06-23

View on ClinicalTrials.gov More Tobacco Use Disorder trials

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change in imbalance between goal-directed and habitual behavior

Timeframe: 2 time points: before and after 6 weeks SCP

Change in implicit smoking-related associations

Timeframe: 3 time points: before and after 6 weeks SCP plus after 3 months

Change in attentional bias to smoking cues

Timeframe: 3 time points: before and after 6 weeks SCP plus after 3 months

Change in smoking urges

Timeframe: 3 time points: before and after 6 weeks SCP plus after 3 months

Change in working memory capacity

Timeframe: 3 time points: before and after 6 weeks SCP plus after 3 months

Change in planning ability

Timeframe: 3 time points: before and after 6 weeks SCP plus after 3 months

Change in cognitive flexibility

Timeframe: 3 time points: before and after 6 weeks SCP plus after 3 months