CompletedPhase 3

Immunonutrition and Carbohydrate Loading Strategies in Breast Reconstruction

United States125 participantsStarted 2019-02-01

Plain-language summary

This study is designed to test the following hypothesis: patients undergoing immediate alloplastic and autologous breast reconstruction following mastectomy that receive preoperative immunonutrition will experience a reduction in wound complications in the 30-day postoperative period compared to a standard of care control group (retrospective chart review) of 264 (132 alloplastic + 132 autologous) consecutive breast reconstruction patients prior to 5/25/2018.

Who can participate

Age range18 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Medically cleared to undergo oncologic resection and breast reconstructive surgery (including associated anesthesia) at the University of Wisconsin Hospital * Undergoing unilateral or bilateral immediate alloplastic or autologous breast reconstruction by Drs. Afifi, Garland, Gast, Michelotti, Poore, Rao, or Siebert Exclusion Criteria: * Pregnant or breast-feeding women * Incarcerated women * Males * Individuals unable to give consent due to another condition such as impaired decision-making capacity * Women with intolerance or allergy to any ingredients contained within the Impact Advanced Recovery formula that prevents safe consumption of this product. * Impact Advanced Recovery is suitable for lactose intolerance, gluten-free, kosher, and halal diets. * We will exclude individuals with galactosemia * Women who are unable to take oral nutritional supplements

What they're measuring

Number of Incidents of Wound Complications 30-days Post-Op

Timeframe: up to 30 days post-op

Trial details

NCT IDNCT03764943

SponsorUniversity of Wisconsin, Madison

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-08-01