Tonsillectomy and adenoidectomy is one of the most common pediatric surgeries, and agitation and severe postoperative pain have been considered a very common complications. Dexmedetomidine mainly inhibits the release of norepinephrine by acting on the α-adrenergic receptor of the brainstem nucleus, which can produce good sedative effects. Hydromorphone has a longer duration of action than fentanyl, and it also has a certain sedative effect. The combination of the two is more conducive to the management of postanesthetic agitation and pain. This study was to compare the effect of different doses of dexmedetomidine combined with hydromorphone in the sedation and analgesia after pediatric tonsillectomy and adenoidectomy.
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extubation time
Timeframe: duration from the time that patients arrived in PACU to the time of extubation, though study completion, average 40 mins
Agitation scores
Timeframe: scores at the time point of 0 minute after extubation
Agitation scores
Timeframe: scores at the time point of 5 minutes after extubation
Agitation scores
Timeframe: scores at the time point of 10 minutes after extubation
Agitation scores
Timeframe: scores at the time point of 15 minutes after extubation
coughing score
Timeframe: scores at the time point of 0 minute after extubation
coughing score
Timeframe: scores at the time point of 5 minutes after extubation
coughing score
Timeframe: scores at the time point of 10 minutes after extubation
coughing score
Timeframe: scores at the time point of 15 minutes after extubation