CompletedNot Applicable

Modified Enhanced Recovery Program in Emergency Surgery (MERES)

Russia122 participantsStarted 2017-07-01

Plain-language summary

Laparoscopic appendectomy (LA) is a widespread surgical procedure. Patients may develop considerable postoperative pain and dyspepsia resulting in prolong in-hospital stay. Almost 10% of patients develop postoperative complications. Enhanced recovery after surgery (ERAS) program has proven its effectiveness in elective surgery and can theoretically improve outcomes of LA. To date there is no ERAS program for LA. The aim of the study was to investigate the safety and efficacy of a modified ERAS protocol in LA.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with any stage of acute appendicitis except 3B according to Gomes classification; * Class I-II surgical patients according to the classification of The American Society of Anesthesiologists (ASA). Exclusion Criteria: * Patient refusal to participate in the study or to sign the informed consent form; * Language barrier; * Transfer to the intensive care unit (ICU) after surgery; * ASA class ≥ III; * Conversion to open procedure; * Appendicular mass found during laparoscopy; * Gomes 3B appendicitis requiring immersion of the appendicular stump; * Pregnancy.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Postoperative length of stay (pLOS)

Timeframe: 30 days

Trial details

NCT IDNCT03754777

SponsorPirogov Russian National Research Medical University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-12-01

View on ClinicalTrials.gov More Acute Appendicitis trials