Study to analyze electronic medical records of women using an intrauterine device (IUD). The study was required by the FDA for the marketed IUD Mirena (US Post-marketing requirement; short name of study: APEX IUD). The study analyzed the risks that the IUD was expelled or perforated the womb for the following group comparisons: * Women who were breastfeeding at the time of IUD insertion and within 52 weeks postpartum versus women who were not breastfeeding at the time of IUD insertion and within 52 weeks postpartum. * Women who had a first observed IUD insertion within different time periods after childbirth (i.e., ≤ 6 weeks, \> 6 weeks and ≤ 14 weeks, \> 14 weeks and ≤ 52 weeks) versus women who had their first observed IUD insertion more than 52 weeks after childbirth, including women without a recorded delivery within the past 52 weeks. An additional analysis involved 5-level postpartum timing (i.e., 0 to 3 days, 4 days to ≤ 6 weeks, \> 6 weeks to ≤ 14 weeks, \> 14 weeks to ≤ 52 weeks) versus the \> 52 week postpartum group. The study also analyzed the risks that the IUD was expelled or perforated the womb for different types of IUDs. In addition, the study aimed to assess the following interactions: * The extent to which the type of IUD (IUDs releasing the hormone LNG versus Copper IUDs) modified the risk that an IUD was expelled or perforated the womb in relation to breastfeeding and/ or in relation to the point in time when the IUD was inserted after childbirth. * The extent to which the breastfeeding status modified the risk that an IUD was expelled or perforated the womb in relation to the point in time when the IUD was inserted after childbirth.
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Crude Incidence Rate of Uterine Perforation Stratified by Breastfeeding Status Among Women Within 52 Weeks Postpartum-first Observed IUD Insertions
Timeframe: Up to 11 years
Cumulative Incidence of Uterine Perforation Stratified by Breastfeeding Status Among Women Within 52 Weeks Postpartum-first Observed IUD Insertions
Timeframe: At 1 year and 5 years of follow-up
Adjusted Hazard Ratio (HR) for Breastfeeding Status and Uterine Perforation-first Observed IUD Insertions
Timeframe: Up to 11 years
Crude Incidence Rate of Uterine Perforation Categorized by Postpartum Timing-first Observed IUD Insertions
Timeframe: Up to 11 years
Cumulative Incidence of Uterine Perforation Categorized by Postpartum Timing-first Observed IUD Insertions
Timeframe: At 1 year and 5 years of follow-up
Adjusted Hazard Ratio (HR) for Postpartum Timing and Uterine Perforation-first Observed IUD Insertions
Timeframe: Up to 11 years
Adjusted Hazard Ratio (HR) for Postpartum Timing Risk 14-week Cut Point and Uterine Perforation-first Observed IUD Insertions
Timeframe: Up to 11 years
Adjusted Hazard Ratio (HR) for Postpartum Timing Risk 36-week Cut Point and Uterine Perforation-first Observed IUD Insertions
Timeframe: Up to 11 years
Adjusted Incidence Rate Ratio (IRR) for Uterine Perforation-first Observed IUD Insertions
Timeframe: At 1 year and 5 years of follow-up
Adjusted Incidence Rate Difference (IRD) for Uterine Perforation-first Observed IUD Insertions
Timeframe: At 1 year and 5 years of follow-up
Crude Incidence Rate of Uterine Perforation Stratified by IUD Type-first Observed IUD Insertions
Timeframe: Up to 11 years
Cumulative Incidence of Uterine Perforation Stratified by IUD Type-first Observed IUD Insertions
Timeframe: At 1 year and 5 years of follow-up
Adjusted Hazard Ratio (HR) for IUD Type and Uterine Perforation-first Observed IUD Insertions
Timeframe: Up to 11 years
Crude Incidence Rate of Uterine Perforation Stratified by Menorrhagia Status-first Observed IUD Insertions
Timeframe: Up to 11 years
Cumulative Incidence of Uterine Perforation Stratified by Menorrhagia Status-first Observed IUD Insertions
Timeframe: At 1 year and 5 years of follow-up
Adjusted Hazard Ratio (HR) for Menorrhagia Status and Uterine Perforation-first Observed IUD Insertions
Timeframe: Up to 11 years
Effect Modification of Breastfeeding Status on Postpartum Timing for Uterine Perforation
Timeframe: Up to 11 years
Effect Modification of IUD Type on Breastfeeding Status for Uterine Perforation
Timeframe: Up to 11 years
Effect Modification of IUD Type on Postpartum Timing for Uterine Perforation
Timeframe: Up to 11 years