CompletedNot Applicable

ENGAGE for Brain Health

United States25 participantsStarted 2019-01-01

Plain-language summary

Age-related cognitive decline has a profound impact on the daily functioning of older adults, their families and healthcare systems. Despite its significant personal, societal and economic impact, no pharmacologic therapies presently exist to mitigate age-related cognitive decline. As the population of older adults continues to rapidly increase, the implementation of effective and scalable low-cost interventions that may maintain the cognitive independence of broad populations of older persons are now of urgent public health priority.

Who can participate

Age range60 Years – 89 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * • Men and Women age 60-89 years, community-dwelling, ambulatory * Presence of MCR syndrome * Sedentary (reporting ≤ 20 min/week of regularly structured physical activity in the past month) * Written permission from PCP for study participation * Willingness to be randomized and participate for 24 weeks Exclusion Criteria: * • Acute or terminal illness * Modified Mini-Mental State Examination Score \<80(\<76 if African American)\* * Myocardial Infarction in the previous 6 months * Symptomatic coronary artery disease * Upper or lower extremity fracture in the previous 6 months * Resting blood pressure \>180/100 mmHg * Unable to communicate due to severe hearing loss or speech disorder * Severe visual impairment that may preclude participation in the study assessments or interventions * Non-English speaking

What they're measuring

Measuring the safety of a 6 month PA or HE intervention in a community setting in older adults with MCR

Timeframe: 6 Months

Measuring the success (feasibility) of integrating clinical exercise programs into real-world community-based settings.

Timeframe: 6 Months

Trial details

NCT IDNCT03750682

SponsorTufts University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-03-13