Active — Not RecruitingNot Applicable

Assessing Feasibility of Prolonged Repetitive Near Infrared Light Stimulation in Early to Mid-Stage Dementia

United States100 participantsStarted 2018-10-15

Plain-language summary

This study will gather data to see if infrared and near infrared light frequency can increase the activity of brain cells and provide support for the cell's ability to repair and protect themselves against further damage.

Who can participate

Age range

50 Years – 85 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Aged 50-85 years with an independently provided diagnosis of dementia, probable Alzheimer's type. * Dementia symptoms not greater than early to mid-stage dementia * Generally healthy as indicated by recent physical examination within the last 6 months * If labs are available within the last 6 months, renal function, hepatic function, cardiac function should be normal Exclusion Criteria: * Diagnosed actively growing intracranial pathology (tumors etc.) * Misusing illegal substances or alcohol * Previous history of stroke * History of aggression or violence * History of major psychiatric illness * No underlying CNS pathology (confined to tumor, epilepsy only)

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Memory Score

Timeframe: Before first treatment, at 4 weeks and then at 8 weeks.

Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog test) test

Timeframe: Before first treatment, at 4 weeks and then at 8 weeks.

Quantitative Electro Encephalography (QEEG)

Timeframe: Before first treatment, at 4 weeks and then at 8 weeks.

Trial details

NCT IDNCT03750409

SponsorBaylor Research Institute

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-08-27

View on ClinicalTrials.gov More Mild to Moderate Dementia trials

Who can participate

Age range

50 Years – 85 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Memory Score

Timeframe: Before first treatment, at 4 weeks and then at 8 weeks.

Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog test) test

Timeframe: Before first treatment, at 4 weeks and then at 8 weeks.

Quantitative Electro Encephalography (QEEG)

Timeframe: Before first treatment, at 4 weeks and then at 8 weeks.