CompletedNot Applicable

Cardiovascular Status of Children 5 Years After Kawasaki Disease

Poland61 participantsStarted 2019-01-01

Plain-language summary

The aim of present study is to determine cardiovascular status of children who had KD in past and to identify possible biochemical markers of cardiovascular damage in those patients. In this cross-sectional study children with history of KD will be examined 5 years after receiving intravenous immunoglobulin treatment (IVIG) and compared to healthy controls in terms of: serum levels of endothelial injury markers (circulating endothelial cells, galectin-3, soluble VCAM), peripheral blood pressure, central blood pressure, arterial stiffness parameters (measured by applanation tonometry), carotid intima media thickness (cIMT), capillaroscopy and echocardiography.

Who can participate

Age range5 Years – 15 Years

SexALL

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Inclusion Criteria: * history of KD treated with intravenous immunoglobulin (IVIG) Exclusion Criteria: * any significant comorbidities, * body mass index (BMI) value \> 1 standard deviation (SD) for age and gender, * height \< 120 cm at the time of cardiovascular assessment.

What they're measuring

CEC in children 5 years after KD

Timeframe: 5 years

Arterial stiffness in children 5 years after KD

Timeframe: 5 years

Central blood pressure in children 5 years after KD

Timeframe: 5 years

Trial details

NCT IDNCT03750123

SponsorMedical University of Warsaw

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-09-28

View on ClinicalTrials.gov More Vasculitis, Systemic trials