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Detachable String Magnetically Controlled Capsule Endoscopy for Detecting High-risk Varices in Compensated Cirrhosis

China105 participantsStarted 2018-11-09

Plain-language summary

Gastroesophageal varices is a serious complication of compensated advanced chronic liver disease (cACLD). Primary prophylaxis to reduce the risk of variceal haemorrhage is recommended if high-risk varices (HRV) are detected. We performed this study to compare the accuracy, patients' satisfaction and safety of detection of HRV by detachable string magnetically controlled capsule endoscopy (DS-MCCE) with esophagogastroduodenoscopy (EGD) as the standard.

Who can participate

Age range18 Years – 75 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * age 18-75 years; * confirmed cirrhosis based on liver biopsy or clinical findings; * compensated cirrhosis; * scheduled to undergo esophagogastroduodenoscopy; * estimated survival time\> 24 months, and model for end-stage liver disease (MELD) score\< 19; * with written informed consent. Exclusion Criteria: * contradictions for capsule endoscopy; * contradictions for standard magnetic resonance imaging examination such as the presence of surgical metallic devices; * pregnancy or unknown pregnancy status.

What they're measuring

Diagnostic accuracy of magnetically controlled capsule endoscopy for the risk of variceal bleeding

Timeframe: 1 day

Trial details

NCT IDNCT03749954

SponsorNanfang Hospital, Southern Medical University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2019-12-03

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