CompletedEarly Phase 1

Effect of Addition of Dexmedetomidine During Ultrasound Guided Bilateral Single Shot Erector Spinae Plane Block in Patients Undergoing Posterior Lumbar Interbody Fusion Under General Anesthesia

Egypt40 participantsStarted 2016-01-01

Plain-language summary

Posterior lumbar interbody fusion (PLIF) is the management of choice in double level lumbar (L) spondylolisthesis (L3-L5) after ineffective conservative treatment. We evaluated bilateral ultrasound (US)-guided single shot erector spinae plane (ESP) block at the level of lumbar 3 (L3) vertebra with or without dexmedetomidine (Dex).

Who can participate

Age range18 Years – 60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * belonged to the American Society of Anesthesiologists (ASA) physical status I or II * either sex * aged 18-60 years * body mass index less 35 kg/m2 * complaining from double level lumbar spondylolisthesis (L3-L5) * scheduled for elective surgical intervention aimed at lumbar spine fixation by PLIF - under general anesthesia. Exclusion Criteria: * obesity (body mass index \> 35 kg/m2) * infection of the skin at the site of the needle puncture * allergies to either of the study drugs * bleeding disorder * and recent use of opioid.

What they're measuring

changes in Post-Anesthesia Care Unit (PACU) length of stay

Timeframe: at 1hours, 6hours, 12hours, and 24 hours after the operation

changes in the total dose of postoperative analgesics need

Timeframe: at 1hours, 6hours, 12hours, and 24 hours after the operation

changes in postoperative visual analogue score (VAS)

Timeframe: at 1hours, 6hours, 12hours, and 24 hours after the operation

changes in recovery time

Timeframe: at 1hours, 6hours, 12hours, and 24 hours after the operation

Trial details

NCT IDNCT03746418

SponsorTanta University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-01-01

View on ClinicalTrials.gov More Double Level Lumbar Spondylolisthesis (L3-L5) trials

Plain-language summary

Who can participate

Age range18 Years – 60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

changes in Post-Anesthesia Care Unit (PACU) length of stay

Timeframe: at 1hours, 6hours, 12hours, and 24 hours after the operation

changes in the total dose of postoperative analgesics need

Timeframe: at 1hours, 6hours, 12hours, and 24 hours after the operation

changes in postoperative visual analogue score (VAS)

Timeframe: at 1hours, 6hours, 12hours, and 24 hours after the operation

changes in recovery time

Timeframe: at 1hours, 6hours, 12hours, and 24 hours after the operation