CompletedNot Applicable

Time Restricted Feeding on Weight Loss and Cardio-protection (TREATY Trial)

China139 participantsStarted 2018-11-30

Plain-language summary

Time restricted feeding (TRF) is a novel type of intermittent calorie restriction diet that involves eating a daily period of 8 hours or less. This is a randomized controlled trial to evaluate the effect of time restricted feeding (TRF) on weight loss and cardiometabolic risk factors in obese adults over 12 months compared to continuous energy restriction (CER).

Who can participate

Age range18 Years – 75 Years

SexALL

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Inclusion criteria

✓. Male of female aged between 18 and 75 years old;
✓. Body mass index (BMI)of 28.0 to 45.0 kg/m2;

Exclusion criteria

✕. History of HIV, hepatitis B or C (self-report) or active pulmonary tuberculosis;
✕. Diagnosis of type 1 and type 2 diabetes;
✕. History of malignant tumors;
✕. Serious liver dysfunction or chronic kidney disease (AST or ALT \> 3 times the upper limit of normal, or eGFR\<30 ml/min/1.73 m2);
✕. History of serious cardiovascular or cerebrovascular disease (angina, myocardial infarction or stroke) in the past 6 months;
✕. History of severe gastrointestinal diseases or gastrointestinal surgery in the past 12 months;
✕. History of Cushing's syndrome, hypothyroidism, acromegaly, hypothalamic obesity;
✕. Being a smoker or having been a smoker in the 3 months prior to their screening visit;

What they're measuring

Change in body weight over 12 months

Timeframe: Baseline to 12 months

Trial details

NCT IDNCT03745612

SponsorNanfang Hospital, Southern Medical University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-07-24

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