CompletedPhase 1

Oral Melatonin as Premedication During MAC for Patients Undergoing Loco-regional Chronic Subdural Hematoma Evacuation

Egypt40 participantsStarted 2018-09-05

Plain-language summary

investigators assume that administration of preoperative melatonin will reduce the required dose of propofol in participants undergoing loco-regional chronic subdural hematoma evacuation, it may as well provide better postoperative analgesia and decrease the incidence of delirium.

Who can participate

Age range50 Years – 65 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 50 -65 years * ASA grade I to II * Both sexes * Patients with unilateral chronic subdural hematoma * Patients who are vitally stable * Glascow coma scale 14-15 Exclusion Criteria: * Age below 50 and above 65 years. * Gastro intestinal tract impractabililty. * Patients with any substance abuse. * Patients with hepatic or renal insufficiency. * Patients on antipsychotic, anticonvulsant or anti-parkinsonian medication. * Vitally unstable patients who cannot tolerate propofol sedation. * Patients with known allergies to any of the drugs used.

What they're measuring

To compare propofol consumption among both groups.

Timeframe: 24 hours Postoperative

Trial details

NCT IDNCT03732963

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-11-05

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