UnknownNot Applicable

Comparison Between Standard Deep Anterior Lamellar Keratoplasty (S-DALK) and Intralase Enabled Deep Anterior Lamellar Keratoplaty (IE-DALK)

100 participantsStarted 2015-04-08

Plain-language summary

A prospective comparison between standard deep anterior lamellar keratoplasty (S-DALK) performed manually using a blade (trephine) and femtosecond laser-enabled deep anterior lamellar keratoplasty (IE DALK), where incisions are performed using the femtosecond laser.

Who can participate

Age range18 Years – 70 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age between 18 and 70 years * Either advanced keratoconus or corneal scarring requiring a deep anterior lamellar keratoplasty Exclusion Criteria: * Previous keratoplasty * Advanced glaucoma * Any other retinal or optic nerve pathology that could potentially affect visual outcome * Strabismus or amblyopia * Significant limbal stem cell deficiency (invlolving \> 3 limbal clock hours) * Active autoimmune disease.

What they're measuring

Change from preoperative topographical corneal astigmatism

Timeframe: preoperatively, 6, 12 and 15 months postoperatively

Trial details

NCT IDNCT03732599

SponsorUniversity of Toronto

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-12-31

View on ClinicalTrials.gov More DALK Corneal Transplant trials