Active — Not RecruitingNot Applicable

Root Canal Treatment With TotalFill® Bioceramic Sealer and AH Plus® Sealer

Singapore170 participantsStarted 2018-08-13

Plain-language summary

The study design is a double blinded randomized controlled trial and 170 subjects (teeth) , 85 in each of the 2 groups, will be enrolled from the patients at the NUH dental centre endodontic unit. The study aims to assess how the use of TotalFill® bioceramic sealer affects the healing outcome of apical periodontitis compared to a control AH plus®. Conventional root canal treatment will be done during this study. Radiographs will be taken at each study visit during the study for root canal. The preoperative, postoperative and review clinical and radiographic data will be analysed.

Who can participate

Age range21 Years – 95 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * A preoperative periapical radiograph will be required for diagnosis. * Subjects at least 21 years old. * Medically healthy * In a patient with multiple teeth requiring root canal treatment, only 1 tooth from each side will be included and selected at random. Exclusion Criteria: * Patient below 21 years old * Pregnant women. * Patients with autoimmune diseases and uncontrolled diabetes. * Teeth with periodontal probing depths of 5mm or more. * Incomplete root formation that is detected radiographically. * Cracked teeth * Teeth are deemed to have poor restorative prognosis. * Teeth with adjacent teeth on the same side that require root canal treatment

What they're measuring

Change in the status of periapical lesion size

Timeframe: comparison of the periapical lesion size at baseline, 6 month and 12 month

Trial details

NCT IDNCT03732170

SponsorNational University Hospital, Singapore

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-06-30