Effect of Topical Sulforaphane on Skin Aging and With Ultraviolet and Visible Light Exposure

Inclusion Criteria: * Participants must be over the age of 18 years old with healthy skin or moderate degree of photoaging/intrinsic aging; * Must be healthy enough to undergo skin biopsy, light irradiation, and other study procedures in the opinion of the investigator; * Must be willing to comply with the requirements of the protocol; * Must have the ability to understand and communicate with the investigator; * Participant must provide informed consent. Exclusion Criteria: * Subjects who are unable to provide informed consent; * Subject with significant medical history or current skin diseases that the investigator feels is not safe for study participation; * Subjects who have been treated with systemic retinoids or steroids within the past month prior to entry to the study; * Subjects who have been treated with topical steroids, retinoids or other topical drugs used within 2 weeks prior to entry to the study; * Recently treated or current skin diseases that would affect clinical evaluation and biopsy; * Subjects with a known allergy to broccoli. * Presence or suspicion of bleeding disorder or diathesis which would complicate biopsy. * Subjects with a history of excessive scar or keloid formation in the past 10 years. * Pregnant or nursing subjects (self-reported). * Subjects with known allergy to anesthetics used. * Patients with history of investigational drug use in the 30 days prior to entry into the study.