The AbsorbaSeal Vascular Closure Device Trial

Inclusion Criteria: * Patient is between 18 and 85 years of age * Male and Female * Patient/legal representative provides written informed consent * Patient is scheduled for a coronary or peripheral diagnostic or interventional procedure * Patient is able to undergo emergent vascular surgery if a complication related to the VCD necessitates such surgery * Patient has a 6 french arterial puncture located in the common femoral artery * Target vessel has a lumen diameter ≥ 5 mm * Patient is willing and able to complete follow-up * Catheterization procedure is planned and elective Exclusion Criteria: * Prior target artery closure with any closure device or closure with manual compression ≤ 30 days prior to the cardiac or peripheral catheterization procedure * Patients with a history of significant bleeding or with any known or documented bleeding disorders, such as Thrombocytopenia (with \< 100,000 platelet count), Von Willebrand's disease, anemia (Hgb \< 10 g/dL, Hct \< 30%), thrombasthenia, decreased fibrinogen (\< 200 mg/dL), and Factor V deficiency * Acute ST-elevation myocardial infarction ≤ 48 hours prior to the cardiac or peripheral catheterization procedure * Patient is ineligible for in-lab catheterization lab introducer sheath removal * Concurrent participation in another investigational device or drug trial * Thrombolytic therapy (e.g. streptokinase, urokinase, t-PA) ≤ 24 hours prior to the cardiac or peripheral catheterization procedure * Evidence of a preexisting …