Study of Pembrolizumab in Patients With Early-Stage NK/T-cell Lymphoma, Nasal Type

Inclusion Criteria: * Histologic diagnosis of extranodal NK/T, nasal type cell lymphoma at the enrolling institution * 18 years of age on day of signing informed consent * Have a performance status of ≤ 1 on the ECOG Performance Scale * Have measurable disease by PET/CT * Demonstrate adequate organ function as defined below: RENAL: Serum Creatinine ≤ 1.5 x upper limit of normal (ULN) OR Measured or calculated creatinine clearance (GFR can also be used in place of creatinine or CrCL) Serum creatinine ≥ 60 mL/min for subject with creatinine levels \> 1.5 x institutional ULN ≤ 1.5 x upper limit of normal (ULN) OR Measured or calculated creatinine clearance (GFR can also be used in place of creatinine or CrCL) ≥ 60 mL/min for subject with creatinine levels \> 1.5 x institutional ULN HEPATIC: Serum total bilirubin ≤ 1.5 x ULN OR Serum total bilirubin ≤ 3 x ULN for subjects with liver metastases AST (SGOT) and ALT (SGPT) ≤ 2.5 x ULN OR AST (SGOT) and ALT (SGPT) ≤ 5 x ULN for subjects with liver metastases CARDIAC: Ejection fraction ≥ 50% PULMONARY: Hemoglobin-adjusted diffusing capacity for carbon monoxide ≥ 50% \- Women of childbearing potential\* must have a negative urine or serum pregnancy test (minimum sensitivity 25 IU/L or equivalent units of HCG) within 72 hours prior to receiving the first dose of study medication * \*A woman of childbearing potential is a sexually mature female who has not undergone a hysterectomy or bilateral oophorectomy; or has not …