Myo-inositol and an Antioxidant Mix for the Treatment of Vietnamese Infertile Men (NCT03726450) | Clinical Trial Compass
UnknownNot Applicable
Myo-inositol and an Antioxidant Mix for the Treatment of Vietnamese Infertile Men
Vietnam55 participantsStarted 2018-11-01
Plain-language summary
The aim of this study is to evaluate if Myo-inositol, N-Acetyl-Cysteine plus a cocktail of antioxidants could be able to increase spermatozoa parameters and reduce semen hyper-viscosity
Who can participate
Age range18 Years – 55 Years
SexMALE
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* BMI \< 29
* One year of unsuccessful sexual intercourses without achieving pregnancy for male factor (idiopathic infertility)
* Normospermia, isolated asthenozoospermia and/or oligoasthenozoospermia
* Semen hyper-viscosity defined as severe, moderate and mild
Exclusion Criteria:
* The absence of spermatozoa production
* Positive presence of leucocyte and inflammation factor in the seminal fluid
* Positive urea test for the presence of bacteria, protozoa and/or fungi infection
* Diagnosis of cryptorchidism
* Diagnosis of Varicocele of grade 2 or higher
* Diagnosis of Diabetes and other pathology causing oxidative stress
* Concentration alterations of the following hormones: LH, FSH, Testosterone, Prolactin, 17b-estradiol
* Abuse of alcohol and controlled substance
* Smoking cigarettes (\>10 cigarettes/day)
* BMI \> 30
What they're measuring
1
change in sperm motility
Timeframe: spermatozoa motility will be analyzed after 3 months of treatment