RecruitingPhase 4

Effect of Theophylline in Pseudohypoparathyroidism

United States100 participantsStarted 2019-11-11

Plain-language summary

The study evaluates the effect of theophylline in 100 subjects with Pseudohypoparathyroidism.

Who can participate

Age range5 Years – 21 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Subjects with known diagnosis of PHP1A and PHP1B * Age \>5 years Exclusion Criteria: * • Significant kidney disease, i.e. any CKD stage * Hypercalciuria * Kidney stones * Severe Heart disease * Uncontrolled seizure disorder * Peptic ulcer * Liver dysfunction * Bleeding disorder * Allergy to theophylline preparation * Muscle disorder * Infection * Any neurologic disease * Chronic drugs interacting with theophylline

What they're measuring

Effect of Theophylline on Bone Age in PHP

Timeframe: 52 weeks

Trial details

NCT IDNCT03718403

SponsorMassachusetts General Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2030-04-10

Contact for this trial

AMITA SHARMA, MD

6177262908 asharma5@mgh.harvard.edu

View on ClinicalTrials.gov More PHP Ia trials