The aim of the present randomized double-blinded placebo-controlled clinical trial is to investigate if melatonin can protect against acute radiation dermatitis in patients with early breast cancer receiving radiation therapy, and whether this has an impact on the patients' quality of life.
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Radiation Therapy Oncology Group's acute radiation morbidity scoring criteria of the skin
Timeframe: Once weekly for 8 weeks
Erythema evaluated through pixel analysis of clinical photographs
Timeframe: Once weekly for 8 weeks
European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Breast symptoms (QLQ-BR23)
Timeframe: Once weekly for 8 weeks