Multi-modal Neuroimaging in Children With Cerebral Palsy or Brachial Plexus Birth Palsy (NCT03712072) | Clinical Trial Compass
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Multi-modal Neuroimaging in Children With Cerebral Palsy or Brachial Plexus Birth Palsy
United States32 participantsStarted 2018-02-01
Plain-language summary
The main goal of this study is to identify abnormal functional and anatomical brain reorganization associated with hand, foot, and shoulder function in children (0-18 years old) with cerebral palsy (CP) due to periventricular white matter injury (PV-WMI) or brachial plexus birth palsy (BPBP) using a multi-modal neuroimaging approach.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Children with Cerebral Palsy should have:
* An evaluation by a pediatric neurologist with a diagnosis of CP due to PV-WMI,
* Absence of any genetic syndrome diagnosis,
* No history of trauma or brain operation,
* Classified as high-functioning (I or II) at the Gross Motor Function Classification System (GMFCS)32.
Children with Brachial Plexus Birth Palsy should have:
* An evaluation by a hand and upper extremity surgeon with a diagnosis of BPBP
* May or may not have undergone primary microsurgical or secondary reconstructive operations prior to this study.
Typically Developing children should have:
* No history of neurological disorder or brain injury.
Exclusion Criteria:
Children will be excluded if they meet any of the follow criteria, determined via their medical and developmental history:
* Having a hard time sitting still,
* Presence of any metal implants,
* Baclofen pumps,
* History of traumatic brain injury or brain operation.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Somatosensory evoked potentials as assessed using MEG