CompletedNot Applicable

Use of Platelet Indices for Prediction of Recurrent Miscarriage

Egypt140 participantsStarted 2019-01-01

Plain-language summary

Platelet indices might be a marker for platelet activation, and thus could predict thrombosis. This might be the cause in some cases of recurrent miscarriage. This study aims to evaluate the use of platelet indices -as a simple test- to predict recurrent miscarriage.

Who can participate

Age range

18 Years – 49 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Women aged 18-49 years.
. Women with history of recurrent miscarriage(two or more consecutive miscarriages)
. Women with history of previous deliveries.

Exclusion criteria

. Pregnant women
. Women with medical disease (e.g. DM, thyroid disorders, hypertension, systemic lupus erythematosus, antiphospholipid antibody syndrome).
. Women with known uterine anomalies.
. Obesity (BMI \>30%).
. Women on anticoagulant medications or antiplatelet medications.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Mean Platelet Volume (MPV)

Timeframe: 1 day (measured once the participant is enrolled in the study & meets the eligibility criteria)

plateletcrit (PCT)

Timeframe: 1 day (measured once the participant is enrolled in the study & meets the eligibility criteria)

Platelet Distribution Width (PDW)

Timeframe: 1 day (measured once the participant is enrolled in the study & meets the eligibility criteria)

Trial details

NCT IDNCT03710226

SponsorRania Hassan Mostafa

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2019-08-30

View on ClinicalTrials.gov More Recurrent Miscarriage trials

Who can participate

Age range

18 Years – 49 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Women aged 18-49 years.
. Women with history of recurrent miscarriage(two or more consecutive miscarriages)
. Women with history of previous deliveries.

Exclusion criteria

. Pregnant women
. Women with medical disease (e.g. DM, thyroid disorders, hypertension, systemic lupus erythematosus, antiphospholipid antibody syndrome).
. Women with known uterine anomalies.
. Obesity (BMI \>30%).
. Women on anticoagulant medications or antiplatelet medications.

What they're measuring

Mean Platelet Volume (MPV)

Timeframe: 1 day (measured once the participant is enrolled in the study & meets the eligibility criteria)

plateletcrit (PCT)

Timeframe: 1 day (measured once the participant is enrolled in the study & meets the eligibility criteria)

Platelet Distribution Width (PDW)

Timeframe: 1 day (measured once the participant is enrolled in the study & meets the eligibility criteria)