UnknownPhase 4

Registration of the Study of Reyanning Mixture

144 participantsStarted 2018-10-22

Plain-language summary

The purpose of this study is to evaluate the efficacy and safety of treating with acute tonsillitis using Reyanning mixture alone/in combination with antibiotics, and its function of reducing the use of antibiotics.

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Meet the diagnostic criteria of acute tonsillitis;
✓. Meet the traditional Chinese medicine symptom diagnostic criteria of external wind-heat type and excessive heat in the lung and stomach type;
✓. 18 years≤age≤65 years;
✓. course of disease within 72 hours;
✓. sign informed consent.

Exclusion criteria

✕. common cold,influenza, acute laryngopharyngitis, pharyngeal diphtheria, wensang's isthmitis.
✕. complicated with acute tracheobronchitis,pneumonia,rheumatic fever, acute glomerulonephritis or rheumatic heart disease.
✕. complicated with severe angiocardiopathy, cerebrovascular disease, hemopoietic system disease or psychopath.
✕. liver or kidney function is abnormal(ALT\>1.5 times upper limit of normal; Cr\>upper limit of normal); diabetic.
✕. WBC\<10×109/L and neutrophilic granulocyte percentage\<75%;or WBC ≥20×109/L;
✕. gestational, lactating women or who planning to get pregnant within half a year.
✕. already accept similar traditional Chinese medicine or antibiotic within 48 hours before registered.
✕. joining other clinical trials or allergic to any drug in this trials.

What they're measuring

recovery time

Timeframe: after 3 days of medication

recovery time

Timeframe: after 7 days of medication

recovery rate

Timeframe: after 3 days of medication

recovery rate

Timeframe: after 7 days of medication

antibiotic duration

Timeframe: after 7 days of medication

antibiotic dosage

Timeframe: after 7 days of medication

Trial details

NCT IDNCT03704506

SponsorChina Academy of Chinese Medical Sciences

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-06-30

Contact for this trial

Yanming Xie, BA

86-13911112416 ktzu2018@163.com

View on ClinicalTrials.gov More Acute Tonsillitis trials

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Meet the diagnostic criteria of acute tonsillitis;
✓. Meet the traditional Chinese medicine symptom diagnostic criteria of external wind-heat type and excessive heat in the lung and stomach type;
✓. 18 years≤age≤65 years;
✓. course of disease within 72 hours;
✓. sign informed consent.

Exclusion criteria

✕. common cold,influenza, acute laryngopharyngitis, pharyngeal diphtheria, wensang's isthmitis.
✕. complicated with acute tracheobronchitis,pneumonia,rheumatic fever, acute glomerulonephritis or rheumatic heart disease.
✕. complicated with severe angiocardiopathy, cerebrovascular disease, hemopoietic system disease or psychopath.
✕. liver or kidney function is abnormal(ALT\>1.5 times upper limit of normal; Cr\>upper limit of normal); diabetic.
✕. WBC\<10×109/L and neutrophilic granulocyte percentage\<75%;or WBC ≥20×109/L;
✕. gestational, lactating women or who planning to get pregnant within half a year.
✕. already accept similar traditional Chinese medicine or antibiotic within 48 hours before registered.
✕. joining other clinical trials or allergic to any drug in this trials.

What they're measuring

recovery time

Timeframe: after 3 days of medication

recovery time

Timeframe: after 7 days of medication

recovery rate

Timeframe: after 3 days of medication

recovery rate

Timeframe: after 7 days of medication

antibiotic duration

Timeframe: after 7 days of medication

antibiotic dosage

Timeframe: after 7 days of medication