Not Yet RecruitingNot Applicable

Urothelium Tissue Engineering Using Biopsies From Transurethral Resection of Prostate

365 participantsStarted 2018-10

Plain-language summary

Different clinical conditions can require urinary bladder augmentation or replacement. Tissue engineered bladder has been clinically evaluated but is not recommended due to diverse side effects. Thus, there is a real interest for the development of regenerative approach with innovative scaffolds and cell transplantation. The investigators propose the use of urothelial cells obtained by Trans-Urethral Resection of Prostate or bladder (TURP) to obtain a tissue engineered urothelium in association with different scaffolds.

Who can participate

Age range18 Years

SexMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patient needing a Transurethral Resection of Prostate (TURP) * Weight of prostate (evaluated by ultrasonography)greater than or equal to 30 grams * Affiliation to a social security system * Patient over the age of majority * Patient receiving complete information on research organization without opposition to the use of biological specimen Exclusion Criteria: * Patient for whom no TURP is realized during endoscopic procedure * Patient for whom no resection is realized on the bladder neck * Patient with prostate weight estimated under 30 grams * Patient who opposed to the realization of the study

What they're measuring

Histological analysis of biopsy.

Timeframe: 6 month

Trial details

NCT IDNCT03698721

SponsorCentral Hospital, Nancy, France

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-10

Contact for this trial

Nicolas Berte, Dr

00333673004195 n.berte@chru-nancy.fr

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