CompletedNot Applicable

The INSPIRE-ASP UTI Trial

United States55,412 participantsStarted 2018-10-01

Plain-language summary

The INSPIRE-ASP UTI trial is a cluster-randomized controlled trial of HCA hospitals comparing routine empiric antibiotic stewardship practices with real-time precision medicine computerized physician order entry smart prompts providing the probability that a non-critically ill adult admitted with UTI is infected with a resistant pathogen. Note: that enrolled "subjects" represents 59 individual HCA hospitals that have been randomized.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Facility Inclusion Criteria: * HCA hospitals admitting adults for UTI * Facility use of MEDITECH as their electronic health record system Facility Exclusion Criteria: \- Note: unit of randomization is the hospital, however the CPOE alert intervention will calculate risk estimates for adults age \>=18 admitted to non-ICU wards and who are ordered to receive extended-spectrum antibiotics for UTI. Prisoners were excluded from prompts and analysis.

What they're measuring

Extended-Spectrum Days Of Antibacterial Therapy (ES-DOT) Per Empiric Day

Timeframe: First 3 days of hospitalization for each patient during 15-month intervention period

Trial details

NCT IDNCT03697096

SponsorHarvard Pilgrim Health Care

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-05-16

Results submitted2024-05-16

View on ClinicalTrials.gov More Urinary Tract Infection (UTI) trials