Visualizing Vascular Mechanisms of Salt Sensitivity (NCT03696433) | Clinical Trial Compass
CompletedNot Applicable
Visualizing Vascular Mechanisms of Salt Sensitivity
United States19 participantsStarted 2019-02-01
Plain-language summary
This study aims to assess the salt sensitive blood pressure response to dietary salt load compared with radiological markers of salt handling.
Who can participate
Age range18 Years – 55 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Identification as black race
* Age between 18 and 55 years
* Body mass index between 25 and \<35 kg/m2
* Normotensive or pre-hypertensive
* Willing to adhere to study diets
* Able to provide informed consent and communicate with study personnel
Exclusion Criteria:
* Prevalent cardiovascular disease or use of medications for cardiovascular disease
* Current or prior history of hypertension or use of blood pressure lowering medications
* Current or prior history of diabetes mellitus or use of anti-diabetic medications
* Prevalent renal disease (eGFR \< 60 ml/min/1.73m2), abnormal serum sodium or potassium
* Current or prior smoker
* Current pregnancy, or use of hormone replacement therapy or oral contraceptive
* Current steroid use
* Contraindications to MRI
* Active infection or open wounds on the top of the feet or hands
What they're measuring
1
Mean Arterial Blood Pressure Following High-salt Diet and Low-salt Diet
Timeframe: Following completion of all dietary supplements and washout, in no less than 21 days.