RecruitingNot Applicable

Non-invasive Glioma Characterization Through Molecular Imaging

United States30 participantsStarted 2019-01-25

Plain-language summary

MRI-based sequences can provide non-invasive quantification of intratumoral 2-hydroxyglutarate (2HG) distribution and tumor cellularity in human gliomas and help guide the development of novel glioma therapies.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adults (≥18 year old) * Subjects with suspected or confirmed gliomas and who will have a medically indicated biopsy or resection of his/her brain lesion. Exclusion Criteria: * Adults unable to consent * Individuals who are not yet adults (infants, children, teenagers) * Pregnant women * Patients unable to have MRI done

What they're measuring

2HG Concentration via 3T MRI Scanner

Timeframe: Day 1

2HG Concentration from tissue samples

Timeframe: Day 1

Trial details

NCT IDNCT03684109

SponsorUniversity of Miami

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-01-31

Contact for this trial

Nathalie Padron

305-243-3530 npadron@med.miami.edu

View on ClinicalTrials.gov More Glioma trials