Low-dose of Ticagrelor and Standard-dose Clopidogrel on Platelet Effects in Chinese Patients With Stable CAD.

Inclusion Criteria: * Patients were eligible to participate if they were aged ≥18 years and ≤ 75 Years * Subjects had documented stable CAD (defned as stable angina pectoris and objective evidence of CAD, a previous MI, or previous revascularization with percutaneous coronary intervention or coronary artery bypass grafting) * Women were required to be postmenopausal or surgically sterile * Patients who were taking clopidogrel or ticagrelor were required to discontinue these agents at least 14 days before randomization Exclusion Criteria: * Acute coronary syndrome (ACS) * planned use of glycoprotein IIb/IIIa receptor inhibitors, adenosine diphosphate (ADP) receptor antagonists other than the study medication, or anticoagulant therapy during the study period * platelet count \<10\*10\^4/ul * creatinine clearance rate \< 30ml/min * diagnosed as respiratory or circulatory instability (cardiac shock, severe congestive heart failure NYHA II-IV or left ventricular ejection fraction \< 40%) * a history of bleeding tendency * allergy to aspirin, ticagrelor or clopidogrel * diabetes patients