Active — Not RecruitingNot Applicable

To Study the Impact of Radiation Treatment After Surgery in Patient With Locally Advanced Thyroid Cancer.

India72 participantsStarted 2013-07

Plain-language summary

This trial deals with cancers of the thyroid gland which are advanced at the local site of thyroid. These cancers are treated with surgery and complete removal of the thyroid gland. But due to advanced nature, there is risk of re-occurrence. Radiotherapy can be used to prevent this re-occurrence. This study attempt to see the effect of radiotherapy in preventing re-occurrence and its side effects in advanced thyroid cancer.

Who can participate

Age range18 Years – 70 Years

SexALL

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Inclusion criteria

✓. Gross extrathyroidal spread into soft tissues of the neck, trachea, esophagus, recurrent laryngeal nerve (constituting stage T4a)
✓. R1/ shave resections (minimal residual disease)
✓. R2 resections (gross residual disease)
✓. Multiple lymph nodes positive(\>2) with perinodal extension at level VI B) Normal baseline haematological and biochemical parameters.

Exclusion criteria

✕. Anaplastic or medullary thyroid cancer
✕. Previous history of radiation
✕. Pregnancy
✕. \< 18 years Patient unwilling to participate in the study.

What they're measuring

locoregional recurrence

Timeframe: after completion of treatment- till 5 years

Trial details

NCT IDNCT03669432

SponsorTata Memorial Hospital

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2026-07

View on ClinicalTrials.gov More Thyroid Cancer Stage IV trials