TerminatedNot Applicable

Activity-Dependent Transspinal Stimulation in SCI

Stopped: COVID

United States10 participantsStarted 2018-08-01

Plain-language summary

Robotic gait training is often used with the aim to improve walking ability in individuals with Spinal Cord Injury. However, robotic gait training alone may not be sufficient. This study will compare the effects of robotic gait training alone to robotic gait training combined with either low-frequency or high-frequency non-invasive transspinal electrical stimulation. In people with motor-incomplete SCI, a series of clinical and electrical tests of nerve function will be performed before and after 20 sessions of gait training with or without stimulation.

Who can participate

Age range18 Years – 65 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria: * Clinical diagnosis of motor incomplete spinal cord injury (SCI). * SCI is above thoracic 12 vertebra. * Absent permanent ankle joint contractures. * SCI occurred 6 months before enrollment to the study. Exclusion criteria: * Supraspinal lesions * Neuropathies of the peripheral nervous system * Degenerative neurological disorders of the spine or spinal cord * Motor complete SCI * Presence of pressure sores * Urinary tract infection * Neoplastic or vascular disorders of the spine or spinal cord * Pregnant women or women who suspect they may be or may become pregnant. * People with cochlear implants, pacemaker and implanted stimulators * People with history of seizures * People with implanted Baclofen pumb

What they're measuring

Plasticity of cortical and corticospinal neuronal circuits

Timeframe: 3 years

Plasticity of spinal neuronal circuits

Timeframe: 3 years

Trial details

NCT IDNCT03669302

SponsorCity University of New York

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-10-01