TerminatedNot Applicable

Activity-Dependent Transspinal Stimulation in SCI

Stopped: COVID

United States10 participantsStarted 2018-08-01

Plain-language summary

Robotic gait training is often used with the aim to improve walking ability in individuals with Spinal Cord Injury. However, robotic gait training alone may not be sufficient. This study will compare the effects of robotic gait training alone to robotic gait training combined with either low-frequency or high-frequency non-invasive transspinal electrical stimulation. In people with motor-incomplete SCI, a series of clinical and electrical tests of nerve function will be performed before and after 20 sessions of gait training with or without stimulation.

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria: * Clinical diagnosis of motor incomplete spinal cord injury (SCI). * SCI is above thoracic 12 vertebra. * Absent permanent ankle joint contractures. * SCI occurred 6 months before enrollment to the study. Exclusion criteria: * Supraspinal lesions * Neuropathies of the peripheral nervous system * Degenerative neurological disorders of the spine or spinal cord * Motor complete SCI * Presence of pressure sores * Urinary tract infection * Neoplastic or vascular disorders of the spine or spinal cord * Pregnant women or women who suspect they may be or may become pregnant. * People with cochlear implants, pacemaker and implanted stimulators * People with history of seizures * People with implanted Baclofen pumb

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Plasticity of cortical and corticospinal neuronal circuits

Timeframe: 3 years

Plasticity of spinal neuronal circuits

Timeframe: 3 years

Trial details

NCT IDNCT03669302

SponsorCity University of New York

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-10-01

View on ClinicalTrials.gov More Spinal Cord Injuries trials