Effect of NK Cell Immunotherapy on Advanced Lung Adenocarcinoma Adenocarcinoma With EGFR Mutation

Inclusion Criteria: The criteriaof the enrollment are as following: (1) expected survival\>6 months; (2) age between35-75 years old; (3) KPS \>45; (4) platelets\>80 × 109/L, WBC\>3 × 109/L, hemoglobin\>90g/L, prothrombin time-international normalized ratio (0.8-1.5), adequate hepatic function (bilirubin \< 20 μM, aminotransferase\<60 U/L) and renal function (serum creatinine \< 130 μM, serum urea \<10 mM); (5) All patients confirmed by pathology and/or imaging; Exclusion Criteria: The absence of level 3 hypertension, severe coronary disease, myelosuppression, respiratory disease, acute or chronic infection, and autoimmune diseases. -