Blossom Smart Expander Technology in Breast Reconstruction in Participants With Breast Cancer Undergoing Mastectomy

Inclusion Criteria: * Diagnosis of breast cancer or reason for prophylactic mastectomy (e.g., BRCA mutation and/or strong family history of breast cancer), both unilateral or bilateral mastectomy * No prior breast surgery (excluding biopsy and lumpectomy) or breast radiation * Ability to understand and the willingness to sign a written informed consent document * No life expectancy restrictions * Eastern Cooperative Oncology Group (ECOG) or Karnofsky performance status will not be employed * No requirements for organ and marrow function Exclusion Criteria: * Recent steroid use * No major medical comorbidities (defined as American Society of Anesthesiologists \[ASA\] III or greater) * No connective tissue disorder * Prior breast surgery, excluding biopsy and lumpectomy * History of or plan for breast radiation * Pregnancy and nursing patients will be excluded from the study * No restrictions regarding use of other investigational agents * No exclusion criteria related to history of allergic reactions * No exclusion criteria relating to concomitant medications or substances that have the potential to affect the activity or pharmacokinetics of the study agent * No other agent-specific exclusion criteria * No exclusion of cancer survivors or those who are human immunodeficiency virus (HIV)-positive