Active — Not RecruitingNot Applicable

Retraining Neural Pathways Improves Cognitive Skills After A Mild Traumatic Brain Injury

United States90 participantsStarted 2023-07-01

Plain-language summary

The proposed study tests the efficacy (Phase II) of 36 30-minute training sessions of PATH neurotraining followed by digit memory exercises to improve working memory, processing speed and attention in mTBI patients rapidly and effectively to provide clinical testing of a therapeutic training for the remediation of cognitive disorders caused by a concussion. This study will contribute to the fundamental knowledge of how to remediate concussions from a mTBI to enhance the health, lengthen the life and reduce the disabilities that result from a mTBI.

Who can participate

Age range18 Years – 60 Years

SexALL

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Inclusion criteria

✓. Referred by Clinician verifying that patient has an mTBI (also includes moderate TBI: those who had a severe TBI with a loss of consciousness more than 30 minutes that is now an mTBI) and has a visual working memory loss as determined by first neuropsychological pre-test administered: The Test of Information Processing Skills (TIPS),
✓. One or more concussions,
✓. Any loss of consciousness from 5- 30 min (not longer than 30 min) to be in mTBI group, otherwise in moderate TBI group.
✓. Any loss of memory for events immediately before or after the accident for 24 hours is in mTBI group, otherwise is in moderate TBI group,
✓. Any alteration of mental state at the time of the accident (e.g. feeling dazed, disoriented, or confused),
✓. Be between the ages of 18 to 60 years, when development and aging are not factors,
✓. Agrees to complete the study after hearing the time commitment involved,
✓. Has corrected 20/20 visual acuity, and normal motor control so can do PATH neurotraining (signal direction that dim gray stripes move by pushing arrow keys on the computer),

Exclusion criteria

What they're measuring

Change in Visual Working Memory

Timeframe: Immediately before begin intervention and 3, 6, and 12 months later.

Trial details

NCT IDNCT03655782

SponsorPerception Dynamics Institute

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2025-08-30

View on ClinicalTrials.gov More MTBI - Mild Traumatic Brain Injury trials