Pulsed Abraxane and Radiotherapy for Improving and Maintaining Ambulation After Cancer-Related Cord Compression

Inclusion Criteria: * Patients with ≤ 37 points per the scoring system listed in the protocol * Histologically or cytologically confirmed diagnosis of cancer not of CNS or spinal column origin. * MRI or CT evidence of metastatic epidural spinal cord compression. * Patients who have started 30 Gy in 10 fractions are not excluded as long as 4 doses of chemotherapy could potentially be given. This means the latest nab-paclitaxel can start is the morning of the third fraction of radiotherapy. Radiotherapy should ideally be delivered at least 6 hours after the nab-paclitaxel infusion started. * At least 18 years of age. * Normal bone marrow and organ function as defined below: * Absolute neutrophil count ≥ 1,500 cells/mm3 * Platelets ≥ 100,000 cells/mm3 (transfusion independent, defined as not receiving platelet transfusions within 7 days prior to blood draw) * Hemoglobin \> 9.0 g/dL * Total bilirubin ≤ 1.5 mg/dL * AST(SGOT)/ALT(SGPT) ≤ 2.5 x IULN * Alkaline phosphatase ≤ 2.5 x IULN (unless bone metastasis is present (\< 5 x IULN) in the absence of liver metastasis) * Creatinine ≤ 1.5 mg/dL * Women of childbearing potential (defined as a sexually mature woman who (1) has not undergone hysterectomy or bilateral oophorectomy or (2) has not been naturally postmenopausal for at least 24 consecutive months) must: * Either commit to true abstinence from heterosexual contact (which must be reviewed on a monthly basis) or agree to use, and be able to comply with, effect…