CompletedNot Applicable

ORI to Reduce Hyperoxia After Out Hospital Cardiac Arrest

Belgium100 participantsStarted 2018-11-08

Plain-language summary

The investigator's research proposal is a randomized controlled study evaluating two different monitoring strategies to titrate FiO2 in order to rapidly and safely achieve optimal SatO2 targets during early ROSC of non-traumatic OHCA in adults. Primary hypothesis: Monitoring transport to hospital of sustained ROSC of OHCA patients using multiple wavelength detectors that allow ORI continuous measurement will reduce hyperoxia and hypoxia burden associated with transport. Secondary hypothesis: Multiple wavelength detectors allowing ORI continuous measurement will reduce hyperoxia at ER admission as measured via blood gas analysis. Tertiary study hypothesis: Multiple wavelength detectors allowing ORI continuous measurement will reduce reperfusion neuronal injury measured through NSE levels at 48h post ROSC

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * out hospital cardiac arrest * non traumatic etiology * ROSC achieved Exclusion Criteria: * less 18 year * traumatic etiology * prisonnier * pregnant woman

What they're measuring

normoxia index

Timeframe: at date of randomisation, from Time of randomisation at ROSC up to time of hospital admission.

Trial details

NCT IDNCT03653325

SponsorCentre Hospitalier Universitaire Saint Pierre

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-01-10

View on ClinicalTrials.gov More Out-Of-Hospital Cardiac Arrest trials