CompletedPhase 4

Oxytocin i.m./i.v. Versus Carbetocin i.v. in Elective Cesarean Sections

Switzerland550 participantsStarted 2018-08-07

Plain-language summary

Objective is to proof non-inferiority of intramyometrial and intravenous oxytocin application compared to intravenous carbetocin for prevention of postpartum hemorrhage in planned, uncomplicated cesarean deliveries.

Who can participate

Age range18 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * elective cesarean section * present informed consent * completed 36 weeks of gestation Exclusion Criteria: * need for intubation (carbetocin is only licensed for epidural or spinal anesthesia) * multiple fetus pregnancy * known coagulopathy * Placenta praevia * morbidly adherent placenta * placental abruption * thrombocyte dysfunction * HELLP-syndrome * preeclampsia * history of uterine atony

What they're measuring

incidence of women with a delta hemoglobin ≥ 30g/l.

Timeframe: 48 hours

Trial details

NCT IDNCT03651882

SponsorUniversity of Zurich

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-01-10

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