Motor Evoked Potentials With Modified Facilitation Technique

Inclusion Criteria for healthy individuals: * Ability to understand the purpose and risks of the study, provide signed and dated informed consent * Between 18 and 65 year of age * No neurologic or psychiatric comorbidity requiring continous treatment * No previous damage of central nervous System Inclusion Criteria for patients: * Ability to understand the purpose and risks of the study, provide signed and dated informed consent * Between 18 and 65 year of age * patients with inflammatory diseases of the central nervous system (CNS) or multiple sclerosis appointed for routine MEP diagnostic at the Department of Clinical Neurophysiology, University Hospital Basel Exclusion Criteria: * Contraindication for measuring of motoric evoked potentials (MEP): metal implants (pacemaker, stents); known epilepsy oder previous epileptic fit * Known disease of the peripheral nervous system (polyneuropathy)