CompletedNot Applicable

Microvascular Effects of Intravenous Esmolol During Postoperative Atrial Fibrillation

25 participantsStarted 2015-12

Plain-language summary

Background: Postoperative atrial fibrillation (POAF) is commonplace after cardiothoracic surgery. A rate control strategy by using short-acting beta blockers is recommended as a first-line therapy in patients without hemodynamic instability. Microcirculatory effects of POAF and esmolol have not been yet investigated. The investigators made the hypothesis that POAF without hemodynamic instability would induce microvascular dysfunction which could be reversed by intravenous esmolol.

Who can participate

Age range18 Years

SexALL

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Inclusion Criteria: * conventional cardiac surgery * thoracic surgery Exclusion Criteria: * Postoperative atrial fibrillation leading to hemodynamic instability

What they're measuring

effects of POAF without hemodynamic instability on near infrared spectroscopy (NIRS) parameters in combination with a vascular occlusion test

Timeframe: Day 7

Trial details

NCT IDNCT03646773

SponsorHospices Civils de Lyon

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2016-09

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