CompletedNot Applicable

Additive Effect of Intravenous Acetaminophen on Postoperative Pain Control

South Korea84 participantsStarted 2018-08-27

Plain-language summary

This study aimed to evaluate the additive effect of acetaminophen on postoperative pain control in patients receiving nefopam and fentanyl-based patient-controlled analgesia. Participants undergoing laparoscopic hysterectomy will be randomly assigned to treatment group or control group. After end of surgery, acetaminophen or normal saline (placebo) will be administered intravenously depending on the group assigned.

Who can participate

Age range19 Years – 80 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients undergoing total laparoscopic hysterectomy due to uterine myoma, cervical cancer, endometriosis, uterine prolapse Exclusion Criteria: * Liver disease (aspartate transaminase OR alanine transaminase \> 80 IU/L) * Chronic kidney disease (GFR \< 30 ml/min/1.73m2) * History of drug allergy * Chronic pain lasting more than 3 months * Conversion to laparotomy * Complex surgery (co-operation with colon surgeon or urologist) * Limitation in expressing pain

What they're measuring

Total volume of administered analgesics during postoperative 24 hours

Timeframe: 24 hours

Trial details

NCT IDNCT03644147

SponsorSeoul National University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-01-06

View on ClinicalTrials.gov More Postoperative Pain trials