Phase II Trial of Fecal Microbiota Transplant (FMT) for VRE and CRE Patients

Inclusion Criteria: * Cognitively intact and willing to provide informed consent * Willing and able to comply with all study procedures for the duration of the study * Age 18 years or older * Two positive stool cultures for CRE or VRE (positive for the same organism on both cultures). The most recent stool culture must be within 14 days of randomization. * Women of childbearing potential in a sexual relationship with men must use an acceptable method of contraception (including, but not limited to, barrier with additional spermicidal foam or jelly, intrauterine device, hormonal contraception started at least 30 days before enrollment into the study, or intercourse with men who underwent a vasectomy) for 4 weeks following completion of the study treatment. * Males must agree to avoid impregnation of women during and for 4 weeks following completion of the study treatment through the use of an acceptable method of contraception (including but not limited to, barrier with additional spermicidal foam or jelly or vasectomy). * Able to take the test capsule successfully with no signs or symptoms of dysphagia. Exclusion Criteria: * Admitted to an intensive care unit (ICU) for medical reasons (not just boarding). Patients residing in a nursing home, long-term care facility or rehabilitation center may be enrolled. * Patient received antibiotics in the last 48 hours. Patients will be eligible to enroll if antibiotic therapy is discontinued for at minimum 48 hours prior to randomi…