UnknownPhase 4

HOPE - A Study to Evaluate the Effect of a Prehabilitation Program on GI Cancer Patients Planning to Undergo Surgery

United States60 participantsStarted 2018-08-01

Plain-language summary

A one-group prospective cohort study design with measures collected pre- and post-intervention. The primary goal of this study is to evaluate the effect of a multimodal prehabilitation preoperative program on changes in frailty in upper gastrointestinal surgical oncology patients.

Who can participate

Age range

25 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * All patients must be patients of Ochsner being seen at the Ochsner Medical Center (OMC). * All patients must be 25 to 80 years of age. * All patients must have a diagnosis of cancer. * \> 10 pound unintentional weight loss within 1 year * Ability to perform grip strength test and Timed Up and Go (TUG) test * Willingness to participate in the study, document compliance, and attend clinical appointments * All patients must be undergoing one of the following major elective surgical oncologic resections with curative intent: * Pancreaticoduodenectomy for pancreatic cancer * Distal pancreatectomy / splenectomy for pancreatic cancer * Esophageal robotic assisted laparoscopic thoracoscopic esophagectomy for esophageal cancer * Laparoscopic or open, partial or total gastrectomy for gastric cancer Exclusion Criteria: * All patients not undergoing oncologic or major resections. * All patients unwilling or unable to answer questionnaires or accept help to answer electronic or paper questionnaires. * All patients that are unable to participate in an activity program. * All patients unable to wear an electronic activity monitoring device. * All patients not wanting to follow a specific nutritional and breathing intervention. * All patients that are not able or wishing to consent.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Frailty Measurement

Timeframe: 4 Weeks

Trial details

NCT IDNCT03642093

SponsorSiobhan Trotter

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-12

View on ClinicalTrials.gov More Pancreatic Cancer trials

Who can participate

Age range

25 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.