UnknownNot Applicable

Pulmonary Rehabilitation for Uncontrolled Asthma Associated With Elevated BMI

United Kingdom180 participantsStarted 2017-05-11

Plain-language summary

Aim to evaluate the impact of a pulmonary rehabilitation (rehab) programme tailored and delivered to overweight and obese patients with difficult asthma on: 1. Asthma related quality of life (primary outcome) and asthma control (secondary outcome) 2. Treatment burden and healthcare usage (secondary outcomes) 3. Physical activity level, exercise tolerance, lung function and inflammation (secondary outcome) 4. Anxiety and depression (secondary outcome)

Who can participate

Age range

18 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Adults aged 18-80 year (smokers, ex-smokers and non-smokers)
. Confirmed asthma as per Global Initiative for Asthma (GINA) guidelines 2015\[4\] with characteristic symptoms and at least one of the following:
. Difficult asthma defined as per Scottish Intercollegiate Guidelines Network(SIGN)/British Thoracic Society(BTS) guideline 2014 as persistent symptoms and/or frequent asthma attacks despite treatment at step 4 or step 5 with either:
. BMI≥25 kg/m2
. MRC dyspnoea scale ≥3/5

Exclusion criteria

. ICU admission +/- mechanical ventilation in the previous year for asthma exacerbation

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

AQLQ- Asthma quality of life questionnaire

Timeframe: 8 weeks

Trial details

NCT IDNCT03630432

SponsorNHS Greater Glasgow and Clyde

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-05-10

Contact for this trial

Douglas C Cowan

01412115451 douglas.cowan@ggc.scot.nhs.uk

View on ClinicalTrials.gov More Asthma trials