Active — Not RecruitingNot Applicable

Personalizing Mediterranean Diet in Children.

Israel200 participantsStarted 2018-12-27

Plain-language summary

Investigating glucose response to Mediterranean and regular diets in healthy children in order to develop specific pediatric machine-learning for predicting the personalized glucose response to food for individual children. The prediction will be based on multiple measurements, including blood tests, personal lifestyle and gut microbiome. This will allow investigators to design personalized Mediterranean machine-learning-based diets which may potentially reduce the burden of disease in adulthood as well as the burden of obesity in the pediatric age.

Who can participate

Age range6 Years – 11 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Healthy children * 6-11 years of age * Tanner 1 • Exclusion criteria: * Acute disease 2 months prior to enrollment * Chronic illness in the past 5 years, including inflammatory, metabolic, neoplastic, congenital and infectious disease. * Use of medications (e.g. Antibiotics/antifungal, PPI, analgesics) and any antibiotics 3 months prior to the first visit, PPI one month prior to the beginning of the study or use of medication during the study. * Treatment with anti-diabetic medications; * Neuro-psychiatric disorders * Cancer and recent anticancer treatment * Eating disorders (Anorexia nervosa. Bulimia nervosa. Binge eating disorder, Night eating syndrome). * Inability of the participant and/or nuclear family to follow and utilize the smartphone application. * Dietary restrictions or specific dietary regimen

What they're measuring

Postprandial glycemic response

Timeframe: 1-3 years

Trial details

NCT IDNCT03627923

SponsorWeizmann Institute of Science

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-12