CompletedNot Applicable

Norepinephrine Addition in Spinal Anesthesia of Caesarean Section

Egypt300 participantsStarted 2020-10-16

Plain-language summary

The objective is to compare efficacy of prophylactic norepinephrine bolus versus Infusion in prevention of hypotension which occurs frequently after spinal anesthesia for caesarean section. The authors hypothesize that prophylactic norepinephrine bolus is as effective as infusion in Prevention of hypotension after spinal anesthesia in caesarean section

Who can participate

Age range18 Years – 45 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 18 - 45 years * American Society of Anesthesiologists physical status classification II or III * Elective caesarean section under spinal anesthesia * Normal singleton pregnancy beyond 36 weeks gestation * Weight 50-100 kg, height 150-180 cm Exclusion Criteria: * Patient refusal * Allergy or hypersensitivity to norepinephrine * Diabetes, excluding gestational diabetes * Preexisting or pregnancy-induced hypertension * Arrhythmia * Cerebrovascular disease * Known fetal abnormality or fetal distress * Any contraindication to spinal anesthesia * Use of monoamine oxidase inhibitors, triptyline or imipramine antidepressants

What they're measuring

Incidence of hypotension

Timeframe: 5 to 15 minutes after giving spinal anesthesia

Trial details

NCT IDNCT03626454

SponsorFayoum University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-01-01

View on ClinicalTrials.gov More Hypotension Drug-Induced trials