CompletedNot Applicable

Norepinephrine Addition in Spinal Anesthesia of Caesarean Section

Egypt300 participantsStarted 2020-10-16

Plain-language summary

The objective is to compare efficacy of prophylactic norepinephrine bolus versus Infusion in prevention of hypotension which occurs frequently after spinal anesthesia for caesarean section. The authors hypothesize that prophylactic norepinephrine bolus is as effective as infusion in Prevention of hypotension after spinal anesthesia in caesarean section

Who can participate

Age range

18 Years – 45 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 18 - 45 years * American Society of Anesthesiologists physical status classification II or III * Elective caesarean section under spinal anesthesia * Normal singleton pregnancy beyond 36 weeks gestation * Weight 50-100 kg, height 150-180 cm Exclusion Criteria: * Patient refusal * Allergy or hypersensitivity to norepinephrine * Diabetes, excluding gestational diabetes * Preexisting or pregnancy-induced hypertension * Arrhythmia * Cerebrovascular disease * Known fetal abnormality or fetal distress * Any contraindication to spinal anesthesia * Use of monoamine oxidase inhibitors, triptyline or imipramine antidepressants

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Incidence of hypotension

Timeframe: 5 to 15 minutes after giving spinal anesthesia

Trial details

NCT IDNCT03626454

SponsorFayoum University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-01-01

View on ClinicalTrials.gov More Hypotension Drug-Induced trials