Effect of a Basic Skin Care Product on the Structural Strength of the Skin

Inclusion Criteria: * Healthy volunteers and/or with stable chronic condition (e.g. controlled hypertension) * Female, * 65 to 85 years, * Caucasian, * Phototype I to III according to the Fitzpatrick classification, * Body Mass Index between 20 and 28 kg/m2, * Non-smoker of at least one year, * Absence of skin diseases or scars in the skin area of interest, * Absence of tattoos in the skin area of interest, * Able to give written informed consent, * Willing and able to fulfill the study requirements Exclusion Criteria: * Known or suspected defect of healing, * Diabetes mellitus * Any acute or chronic pathology that may interfere with the trial conduct, from investigator point of view, * Acute or chronic wounds in the skin area of interest, * Any skin affection which may interfere with the trial assessment, like urticaria,, psoriasis or scar on investigational areas, * Medical history of skin cancer, * History or establishment of diabetes or pre-diabetes, * Any hyper-sensibility to one of the compounds of the investigational product, * Any regular treatment which may affect the blood coagulation and hemostasis (anticoagulant medications, NSAID, etc.) before the suction blister induction (Visit 3 and Visit 5), one NSAID to treat headache within four days is allowed * Any physical treatment (like laser or surgery) on the arms within the last 6 months, * Use of topical or systemic treatment on the investigational areas within the past 4 weeks (topical hyaluronan, anti-inflamma…