CompletedNot Applicable

Can Cognitive Training Decrease Reactive Aggression?

United States90 participantsStarted 2016-08-16

Plain-language summary

The purpose of the study is to examine the effects of cognitive training on emotion regulation, impulse control, and aggression in people with schizophrenia. The study compares a combination of computerized cognitive remediation and social cognition training (CRT+SCT) to cognitive remediation alone (CRT). Study outcomes include multiple measures of aggression, emotion regulation, impulse control, cognition, and symptoms.

Who can participate

Age range18 Years – 60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * diagnosis of schizophrenia or schizo-affective disorder * Age 18-60 * Mini Mental Status Exam score greater/equal to 24 at screening * Auditory and visual acuity adequate to complete cognitive tests * At least a score of 5 or more on the Life History of Aggression (LHA) aggression items or one confirmed assault in the past year * Capacity and willingness to give consent Exclusion Criteria: * Inability to read or speak English * Documented significant disease of the Central Nervous System (CNS) * History of intellectual impairment predating psychosis (e.g., a diagnosis of developmental disability)

What they're measuring

Change in Aggression

Timeframe: Change from baseline in aggression measures up to the end of intervention at 4 months

Trial details

NCT IDNCT03623477

SponsorWeill Medical College of Cornell University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-10-25

View on ClinicalTrials.gov More Schizophrenia trials