A New Nutritional Countermeasure to Prevent the Deconditioning Induced by 60 Days of Antiorthostatic Bed Rest

Inclusion Criteria: * Healthy male volunteer (see below the description of medical tests and laboratory analysis performed at the selection visit), * Age 20 to 45, * No overweight nor excessive thinness with BMI (weight Kg/ height m2) between 22 and 27, * Height between 158 and 190 cm, * No personal nor family past record of chronic or acute disease or psychological disturbances which could affect the physiological data and/or create a risk for the subject during the experiment, * Fitness level assessment: * if age \< 35 years: 35 ml/min./kg \< VO2max \< 60ml/min./kg, * if age \> 35 years: 30 ml/min./kg \< VO2max \< 60ml/min./kg * Active and free from any orthopedic, musculoskeletal and cardiovascular disorders, * Non smokers, * No alcohol, no drug dependence and no medical treatment, * No shift work or travel across more than one time zone in previous 2 months, * Covered by a Social Security system, * Have signed the information consent, * Free of any engagement during the three hospitalization planned periods. Exclusion Criteria: * \- Past record of orthostatic intolerance, * Cardiac rhythm disorders, * Chronic back pains, * History of hiatus hernia or gastro-esophageal reflux, * History of thyroid dysfunction, renal stones, diabetes, migraines, * Past records of thrombophlebitis, family history of thrombosis or positive response in thrombosis screening procedure, * Allergy including xylocaine allergy * Abnormal result for lower limbs echo-doppler, * History or acti…